Validation of Geno-Sen’s Scrub Typhus Real Time Polymerase Chain Reaction Kit by its Comparison with a Serological ELISA Test.
BACKGROUND
In the latest previous, scrub typhus (ST) has been reported from completely different components of India, based mostly on Weil-Felix/enzyme-linked immunosorbent assay (ELISA)/oblique immunofluorescence assay (IFA). Molecular exams are utilized solely by a few researchers.
OBJECTIVE
Evaluation of a new industrial actual time polymerase chain response (PCR) package for molecular analysis of ST by evaluating it with the generally used IgM ELISA is our intention.
METHODS
ST has been reported throughout India together with Puducherry and surrounding Tamil Nadu and recognized as endemic for ST. This research was designed to correlate antibody detection by IgM ELISA and Orientia tsutsugamushi DNA in actual time PCR.
METHODS
ST IgM ELISA (InBios Inc., USA) was carried out for 170 consecutive sufferers who offered with the signs of acute ST throughout 11 months (November, 2015- September, 2016). All 77 of these sufferers with IgM ELISA positivity and 49 of 93 IgM ELISA damaging sufferers have been subjected to actual time PCR (Geno-Sen’s ST actual time PCR, Himachal Pradesh, India).
METHODS
Statistical evaluation for medical and laboratory outcomes was carried out utilizing IBM SPSS Statistics 17 for Windows (SPSS Inc., Chicago, USA). Chi-square take a look at with Yates correction (Fisher’s take a look at) was employed for a small quantity of samples.
Anti-CTLA-4 [9H10] |
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| MBS488589-5x02mg | MyBiosource | 5x0.2mg | 2160 EUR |
Anti-CTLA-4 [9H10] |
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| MBS488590-02mg | MyBiosource | 0.2mg | 520 EUR |
Anti-CTLA-4 [9H10] |
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| MBS488590-5x02mg | MyBiosource | 5x0.2mg | 2160 EUR |
Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) |
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| ICH1084-100mg | ichorbio | 100mg | 2600 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) |
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| ICH1084-25mg | ichorbio | 25mg | 1140 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) |
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| ICH1084-50mg | ichorbio | 50mg | 1860 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) |
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| ICH1084-5mg | ichorbio | 5mg | 370 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Human CTLA-4, FITC, (clone: A3.4H2.H12), (mouse IgG2ak) |
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| MBS520258-01mg | MyBiosource | 0.1mg | 375 EUR |
Anti-Human CTLA-4, FITC, (clone: A3.4H2.H12), (mouse IgG2ak) |
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| MBS520258-5x01mg | MyBiosource | 5x0.1mg | 1450 EUR |
Anti-Human CTLA-4, Purified, (clone: A3.4H2.H12), (mouse IgG2ak) |
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| MBS520259-025mg | MyBiosource | 0.25mg | 465 EUR |
Anti-Human CTLA-4, Purified, (clone: A3.4H2.H12), (mouse IgG2ak) |
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| MBS520259-5x025mg | MyBiosource | 5x0.25mg | 1845 EUR |
Anti-Mouse CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) |
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| ICH1084UL-100mg | ichorbio | 100mg | 3630 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) |
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| ICH1084UL-25mg | ichorbio | 25mg | 1710 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) |
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| ICH1084UL-50mg | ichorbio | 50mg | 2530 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Anti-Mouse CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) |
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| ICH1084UL-5mg | ichorbio | 5mg | 500 EUR |
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Description: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4 |
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Ctla4 hamster monoclonal antibody, clone 9H10, Purified |
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| AM08061PU-N | Origene Technologies GmbH | 500 µg | Ask for price |
Ctla4 hamster monoclonal antibody, clone 9H10, Low Endotoxin |
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| AM08061LE-N | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse Anti-Human CTLA-4 monoclonal antibody, clone NN17 |
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| CABT-ZB785 | Creative Diagnostics | 50 μl | 456 EUR |
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Description: Mouse |
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Mouse Anti-Human CTLA-4 monoclonal antibody, clone JID115 |
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| CABT-L2927-100uL500uL | Creative Diagnostics | 100 uL, 500 uL | 602.4 EUR |
Mouse Anti-Human CTLA-4 monoclonal antibody, clone JID115 |
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| CABT-L2927 | Creative Diagnostics | 100 µl, 500 µl | Ask for price |
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Description: Mouse |
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Mouse Anti-Mouse CTLA-4 (CD152) Monoclonal antibody, clone 9D9 |
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| CABT-L4442-1mg | Creative Diagnostics | 1 mg | 1076.4 EUR |
Mouse Anti-Mouse CTLA-4 (CD152) Monoclonal antibody, clone 9D9 |
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| CABT-L4442-5mg | Creative Diagnostics | 5 mg | 2886 EUR |
Mouse Anti-Mouse CTLA-4 (CD152) Monoclonal antibody, clone 9D9 |
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| CABT-L4442 | Creative Diagnostics | 1 mg; 5 mg | Ask for price |
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Description: Mouse |
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Mouse Anti-Human CTLA-4 (CD152) Monoclonal antibody, clone BN13 |
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| CABT-L4463-1mg | Creative Diagnostics | 1 mg | 1076.4 EUR |
Mouse Anti-Human CTLA-4 (CD152) Monoclonal antibody, clone BN13 |
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| CABT-L4463-5mg | Creative Diagnostics | 5 mg | 2886 EUR |
Mouse Anti-Human CTLA-4 (CD152) Monoclonal antibody, clone BN13 |
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| CABT-L4463 | Creative Diagnostics | 1 mg; 5 mg | Ask for price |
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Description: Mouse |
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Mouse monoclonal antibody to Mouse CTLA-4 (CD152) (Clone 9D9) |
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| ab-131-131 | Affinitylmmuno | 500 µg | 290 EUR |
ALK rat monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA801099 | Origene Technologies GmbH | 100 µl | Ask for price |
ALK rat monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA801099S | Origene Technologies GmbH | 30 µl | Ask for price |
PTGS2 mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA805365 | Origene Technologies GmbH | 100 µl | Ask for price |
PTGS2 mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA805365S | Origene Technologies GmbH | 30 µl | Ask for price |
Anti-Human CTLA-4 Antibody |
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| 101-M345 | ReliaTech | 100 µg | 399 EUR |
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Description: CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28. |
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Anti-Mouse CTLA-4 Antibody |
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| 103-M351 | ReliaTech | 100 µg | 399 EUR |
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Description: CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28. |
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Hamster monoclonal antibody to Mouse CTLA-4 (CD152) (Clone UC10-4F10-11) |
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| ab-131-130 | Affinitylmmuno | 500 µg | 290 EUR |
RNF144B (IBRDC2) mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA500704 | Origene Technologies GmbH | 100 µl | Ask for price |
RNF144B (IBRDC2) mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA500704S | Origene Technologies GmbH | 30 µl | Ask for price |
CTLA-4 |
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| ant-116 | ProSpec Tany | 0.5mg | 275 EUR |
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Description: Hamster Anti Mouse CTLA-4 (CD152) |
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CTLA-4 |
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| MBS201214-005mL | MyBiosource | 0.05mL | 275 EUR |
CTLA-4 |
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| MBS201214-01mL | MyBiosource | 0.1mL | 360 EUR |
CTLA-4 |
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| MBS201214-5x01mL | MyBiosource | 5x0.1mL | 1375 EUR |
Mouse Anti-Mouse CTLA4 IgG2a Monoclonal Antibody, Clone 2H9G9 |
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| 7133 | Chondrex | 2 mg/ml x 5.0 ml | 524 EUR |
CTLA-4 Antibody |
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| MBS344197-01mLConcentrate | MyBiosource | 0.1mL(Concentrate) | 225 EUR |
CTLA-4 Antibody |
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| MBS344197-1mLConcentrate | MyBiosource | 1mL(Concentrate) | 905 EUR |
CTLA-4 Antibody |
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| MBS344197-7mLRTU | MyBiosource | 7mL(RTU) | 320 EUR |
Hamster Anti CTLA-4 (CD152) Antibody |
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| 20-abx137133 | Abbexa |
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JUN (c-Jun ) mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA800593 | Origene Technologies GmbH | 100 µl | Ask for price |
JUN (c-Jun ) mouse monoclonal antibody, clone OTI9H10 (formerly 9H10) |
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| TA800593S | Origene Technologies GmbH | 30 µl | Ask for price |
Anti-Human CD152 (CTLA-4) PE |
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| MBS696970-100Tests | MyBiosource | 100Tests | 345 EUR |
Anti-Human CD152 (CTLA-4) PE |
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| MBS696970-25Tests | MyBiosource | 25Tests | 205 EUR |
Anti-Human CD152 (CTLA-4) PE |
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| MBS696970-5x100Tests | MyBiosource | 5x100Tests | 1510 EUR |
Anti-Mouse CD152 (CTLA-4) PE |
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| MBS696974-0025mg | MyBiosource | 0.025mg | 165 EUR |
Anti-Mouse CD152 (CTLA-4) PE |
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| MBS696974-01mg | MyBiosource | 0.1mg | 300 EUR |
Anti-Mouse CD152 (CTLA-4) PE |
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| MBS696974-5x01mg | MyBiosource | 5x0.1mg | 1300 EUR |
APC anti-human CD152 (CTLA-4) |
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| E16FHA152-025 | EnoGene | 25 tests | 373.33 EUR |
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Description: Available in various conjugation types. |
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APC anti-human CD152 (CTLA-4) |
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| E16FHA152-100 | EnoGene | 100 tests | 1152 EUR |
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Description: Available in various conjugation types. |
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human anti-human CTLA-4 mAb |
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| E409C29-h100 | EnoGene | 100μL | 395 EUR |
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Description: Available in various conjugation types. |
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mouse anti-human CTLA-4 mAb |
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| E409C29-m100 | EnoGene | 100μL | 395 EUR |
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Description: Available in various conjugation types. |
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human anti-human CTLA-4 mAb |
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| E4A09L06 | EnoGene | 50ug | 255 EUR |
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Description: Available in various conjugation types. |
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Anti-Human CD152 (CTLA-4) APC |
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| MBS696971-100Tests | MyBiosource | 100Tests | 485 EUR |
Anti-Human CD152 (CTLA-4) APC |
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| MBS696971-25Tests | MyBiosource | 25Tests | 220 EUR |
Anti-Human CD152 (CTLA-4) APC |
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| MBS696971-5x100Tests | MyBiosource | 5x100Tests | 2140 EUR |
Anti-Mouse CD152 (CTLA-4) APC |
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| MBS696976-0025mg | MyBiosource | 0.025mg | 190 EUR |
Anti-Mouse CD152 (CTLA-4) APC |
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| MBS696976-01mg | MyBiosource | 0.1mg | 340 EUR |
Anti-Mouse CD152 (CTLA-4) APC |
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| MBS696976-5x01mg | MyBiosource | 5x0.1mg | 1490 EUR |
Human anti-Human CTLA-4 mAb |
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| MBS8576839-005mg | MyBiosource | 0.05mg | 325 EUR |
Human anti-Human CTLA-4 mAb |
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| MBS8576839-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
Human anti-Human CTLA-4 mAb |
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| MBS8576839-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
Human anti-Human CTLA-4 mAb |
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| MBS8576839-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
Human anti-Human CTLA-4 mAb |
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| MBS8576839-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
Mouse anti-Human CTLA-4 mAb |
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| MBS8576840-005mg | MyBiosource | 0.05mg | 325 EUR |
Mouse anti-Human CTLA-4 mAb |
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| MBS8576840-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
Mouse anti-Human CTLA-4 mAb |
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| MBS8576840-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
Mouse anti-Human CTLA-4 mAb |
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| MBS8576840-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
Mouse anti-Human CTLA-4 mAb |
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| MBS8576840-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
CTLA4 mouse monoclonal antibody, clone A3.4H2.H12, FITC |
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| AM31866FC-N | Origene Technologies GmbH | 100 µg | Ask for price |
Anti-Mouse CD152/CTLA-4 Antibody |
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| Y300086 | ABM | 100 µl | 215 EUR |
Anti-Human CD152 (CTLA-4) Antibody |
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| MBS4159599-01mL | MyBiosource | 0.1mL | 590 EUR |
Anti-Human CD152 (CTLA-4) Antibody |
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| MBS4159599-5x01mL | MyBiosource | 5x0.1mL | 2395 EUR |
Hamster Anti Mouse CTLA-4 (CD152) |
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| MBS140017-05mg | MyBiosource | 0.5mg | 440 EUR |
Hamster Anti Mouse CTLA-4 (CD152) |
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| MBS140017-1mg | MyBiosource | 1mg | 600 EUR |
Hamster Anti Mouse CTLA-4 (CD152) |
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| MBS140017-5x1mg | MyBiosource | 5x1mg | 2375 EUR |
Biotin anti-human CD152 (CTLA-4) |
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| E16FHB152-050U | EnoGene | 50 μg | 650 EUR |
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Description: Available in various conjugation types. |
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Biotin anti-human CD152 (CTLA-4) |
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| E16FHB152-500U | EnoGene | 500 μg | 1950 EUR |
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Description: Available in various conjugation types. |
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Biotin anti-mouse CD152 (CTLA-4) |
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| E16FMB152-100U | EnoGene | 100 μg | 520 EUR |
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Description: Available in various conjugation types. |
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Purified anti-mouse CD152 (CTLA-4) |
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| E16FMU152-100U | EnoGene | 100 μg | 416 EUR |
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Description: Available in various conjugation types. |
|||
Rat Monoclonal anti-mouse CTLA-4 |
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| mAP-0199 | Angio Proteomie | 100ug | 250 EUR |
Anti-Human CD152 (CTLA-4) Purified |
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| MBS696968-01mg | MyBiosource | 0.1mg | 260 EUR |
Anti-Human CD152 (CTLA-4) Purified |
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| MBS696968-5x01mg | MyBiosource | 5x0.1mg | 1120 EUR |
Anti-Mouse CD152 (CTLA-4) Purified |
|||
| MBS696972-01mg | MyBiosource | 0.1mg | 225 EUR |
Anti-Mouse CD152 (CTLA-4) Purified |
|||
| MBS696972-5x01mg | MyBiosource | 5x0.1mg | 965 EUR |
Mouse Monoclonal anti-human CTLA-4 |
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| hAP-0206 | Angio Proteomie | 100ug | 250 EUR |
Mouse Monoclonal anti-human CTLA-4 |
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| hAP-0206A | Angio Proteomie | 50ug | 400 EUR |
Sheep Polyclonal anti-Human CTLA-4 |
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| hAP-5812 | Angio Proteomie | 50ug | 400 EUR |
CTLA4 mouse monoclonal antibody, clone A3.4H2.H12, Purified |
|||
| AM31866PU-N | Origene Technologies GmbH | 250 µg | Ask for price |
PE Anti-Human CD152 (CTLA-4) (BNI3) |
|||
| MBS4165430-100Tests | MyBiosource | 100Tests | 345 EUR |
PE Anti-Human CD152 (CTLA-4) (BNI3) |
|||
| MBS4165430-5x100Tests | MyBiosource | 5x100Tests | 1295 EUR |
PE-Cy7 anti-human CD152 (CTLA-4) |
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| E16FHN152-025 | EnoGene | 25 tests | 650 EUR |
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Description: Available in various conjugation types. |
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PE-Cy7 anti-human CD152 (CTLA-4) |
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| E16FHN152-100 | EnoGene | 100 tests | 1408.33 EUR |
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Description: Available in various conjugation types. |
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Anti-Mouse CD152 (CTLA-4) PE-Cy7 |
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| MBS696975-0025mg | MyBiosource | 0.025mg | 220 EUR |
Anti-Mouse CD152 (CTLA-4) PE-Cy7 |
|||
| MBS696975-01mg | MyBiosource | 0.1mg | 390 EUR |
Anti-Mouse CD152 (CTLA-4) PE-Cy7 |
|||
| MBS696975-5x01mg | MyBiosource | 5x0.1mg | 1715 EUR |
APC Anti-Human CD152 (CTLA-4) (BNI3) |
|||
| MBS4165208-100Tests | MyBiosource | 100Tests | 450 EUR |
APC Anti-Human CD152 (CTLA-4) (BNI3) |
|||
| MBS4165208-5x100Tests | MyBiosource | 5x100Tests | 1770 EUR |
CTLA-4 Antibody [1E6] |
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| MBS154535-01mg | MyBiosource | 0.1mg | 500 EUR |
CTLA-4 Antibody [1E6] |
|||
| MBS154535-5x01mg | MyBiosource | 5x0.1mg | 2230 EUR |
CTLA-4 Antibody [8A1] |
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| MBS154538-01mg | MyBiosource | 0.1mg | 500 EUR |
CTLA-4 Antibody [8A1] |
|||
| MBS154538-5x01mg | MyBiosource | 5x0.1mg | 2230 EUR |
CTLA-4 Antibody [2G10] |
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| MBS154537-01mg | MyBiosource | 0.1mg | 500 EUR |
CTLA-4 Antibody [2G10] |
|||
| MBS154537-5x01mg | MyBiosource | 5x0.1mg | 2230 EUR |
NE Hamster anti-mouse CD152/CTLA-4 |
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| E16FMY152-500U | EnoGene | 500 μg | 1061.67 EUR |
|
Description: Available in various conjugation types. |
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Anti-Mouse CD152/CTLA-4-UNLB Antibody |
|||
| MBS4151838-01mg | MyBiosource | 0.1mg | 520 EUR |
Anti-Mouse CD152/CTLA-4-UNLB Antibody |
|||
| MBS4151838-5x01mg | MyBiosource | 5x0.1mg | 2090 EUR |
Anti-Mouse CD152/CTLA-4-UNLB Antibody |
|||
| MBS4152501-01mg | MyBiosource | 0.1mg | 520 EUR |
Anti-Mouse CD152/CTLA-4-UNLB Antibody |
|||
| MBS4152501-5x01mg | MyBiosource | 5x0.1mg | 2090 EUR |
CD152 (CTLA-4) Antibody |
|||
| abx021366-02mg | Abbexa | 0.2 mg | 1220.4 EUR |
CD152 Antibody (CTLA-4) |
|||
| GWB-846332 | GenWay Biotech | 0.2 mg | Ask for price |
CTLA-4 Antibody / CD152 |
|||
| R32809 | NSJ Bioreagents | 100 ug | 356.15 EUR |
|
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function. |
|||
CTLA-4 Antibody / CD152 |
|||
| RQ6465 | NSJ Bioreagents | 100ug | 356.15 EUR |
|
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function. |
|||
CTLA-4 Antibody / CD152 |
|||
| RQ5483 | NSJ Bioreagents | 100 ul | 356.15 EUR |
|
Description: The CTLA4 gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq] |
|||
CTLA-4 Antibody / CD152 |
|||
| V7700-100UG | NSJ Bioreagents | 100 ug | 424.15 EUR |
|
Description: This CTLA4 antibody is specific to the soluble form of the protein. CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. |
|||
CTLA-4 Antibody / CD152 |
|||
| V7700-20UG | NSJ Bioreagents | 20 ug | 186.15 EUR |
|
Description: This CTLA4 antibody is specific to the soluble form of the protein. CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. |
|||
CTLA-4 Antibody / CD152 |
|||
| V7700SAF-100UG | NSJ Bioreagents | 100 ug | 424.15 EUR |
|
Description: This CTLA4 antibody is specific to the soluble form of the protein. CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. |
|||
CTLA-4 Antibody / CD152 |
|||
| V4922-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
|
Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4922-20UG | NSJ Bioreagents | 20ug | 160.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4922SAF-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4923-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4923-20UG | NSJ Bioreagents | 20ug | 160.3 EUR |
|
Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4923SAF-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4924-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4924-20UG | NSJ Bioreagents | 20ug | 160.3 EUR |
|
Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4924SAF-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
|
Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4925-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4925-20UG | NSJ Bioreagents | 20ug | 160.3 EUR |
|
Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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CTLA-4 Antibody / CD152 |
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| V4925SAF-100UG | NSJ Bioreagents | 100ug | 363.3 EUR |
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Description: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a member of the CD28 superfamily and is a negative regulator of T cell-mediated immune responses. CTLA-4 expression is induced on the surface of T cells after CD28 binding and activation, and is constitutively expressed on T-regulatory cells, acting as an immune checkpoint inhibitor, downregulating T cell activity. CTLA-4 primarily inactivates T-cell activity by competing with the CD28 costimulatory molecule. CD28 and CTLA-4 share the identical ligands of CD80 and CD86 on antigenpresenting cells; and thus CTLA-4 competes with CD28 function in T-cell survival, proliferation, and recruitment. In particular, CTLA-4 down-modulates CD4+ helper T-cell activity and enhances Treg immunosuppressive functions. CTLA-4 has been shown to play a role in human diseases. CTLA-4 acts as a physiological brake on the activated immune system in order to maintain immune homeostasis. Several suppressive mechanisms for T-cell functions have been attributed to CTLA-4. |
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NE Purified anti-human CD152 (CTLA-4) |
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| E16FHY152-050U | EnoGene | 50 μg | 520 EUR |
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Description: Available in various conjugation types. |
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NE Purified anti-human CD152 (CTLA-4) |
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| E16FHY152-500U | EnoGene | 500 μg | 1820 EUR |
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Description: Available in various conjugation types. |
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Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-5BB57D | GenWay Biotech | 0.5 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-626F92 | GenWay Biotech | 0.5 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-2A8200 | GenWay Biotech | 0.1 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-999BEE | GenWay Biotech | 0.5 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-F3A374 | GenWay Biotech | 0.5 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-E0B3C2 | GenWay Biotech | 0.5 mg | Ask for price |
Hamster Anti-Mouse CD152/CTLA-4, Antibody |
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| GWB-C3E1E0 | GenWay Biotech | 0.5 mg | Ask for price |
CTLA-4/CD152 |
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| MBS370298-01mLConcentrate | MyBiosource | 0.1mL(Concentrate) | 280 EUR |
CTLA-4/CD152 |
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| MBS370298-05mLConcentrate | MyBiosource | 0.5mL(Concentrate) | 465 EUR |
CTLA-4/CD152 |
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| MBS370298-3mLRTU | MyBiosource | 3mL(RTU) | 280 EUR |
CTLA-4/CD152 |
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| MBS370298-5ControlSlides | MyBiosource | 5ControlSlides | 170 EUR |
CTLA-4/CD152 |
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| MBS370298-7mLRTU | MyBiosource | 7mL(RTU) | 360 EUR |
CTLA-4 (CD152) |
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| MBS378137-05mg | MyBiosource | 0.5mg | 410 EUR |
CTLA-4 (CD152) |
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| MBS378137-5x05mg | MyBiosource | 5x0.5mg | 1550 EUR |
CTLA-4 (CD152) |
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| MBS378138-05mg | MyBiosource | 0.5mg | 410 EUR |
CTLA-4 (CD152) |
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| MBS378138-5x05mg | MyBiosource | 5x0.5mg | 1550 EUR |
CTLA-4 (CD152) |
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| MBS378139-05mg | MyBiosource | 0.5mg | 410 EUR |
CTLA-4 (CD152) |
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| MBS378139-5x05mg | MyBiosource | 5x0.5mg | 1550 EUR |
FITC Hamster anti-mouse CD152/CTLA-4 |
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| E16FMF152-500U | EnoGene | 500 μg | 996.67 EUR |
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Description: Available in various conjugation types. |
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Hamster Anti-Mouse CD152/CTLA-4-PE |
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| MBS673516-01mg | MyBiosource | 0.1mg | 300 EUR |
Hamster Anti-Mouse CD152/CTLA-4-PE |
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| MBS673516-5x01mg | MyBiosource | 5x0.1mg | 1200 EUR |
Purified Anti-Human CD152 (CTLA-4) (BNI3) |
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| MBS4165658-01mg | MyBiosource | 0.1mg | 275 EUR |
Purified Anti-Human CD152 (CTLA-4) (BNI3) |
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| MBS4165658-5x01mg | MyBiosource | 5x0.1mg | 980 EUR |
Biotin Hamster anti-mouse CD152/CTLA-4 |
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| E16FMB152-500U | EnoGene | 500 μg | 1256.67 EUR |
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Description: Available in various conjugation types. |
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Hamster Anti-Mouse CD152/CTLA-4-UNLB |
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| MBS673513-05mg | MyBiosource | 0.5mg | 305 EUR |
Hamster Anti-Mouse CD152/CTLA-4-UNLB |
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| MBS673513-5x05mg | MyBiosource | 5x0.5mg | 1225 EUR |
Hamster Anti-Mouse CD152/CTLA-4-FITC |
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| MBS673514-05mg | MyBiosource | 0.5mg | 420 EUR |
Hamster Anti-Mouse CD152/CTLA-4-FITC |
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| MBS673514-5x05mg | MyBiosource | 5x0.5mg | 1740 EUR |
Hamster Anti-Mouse CD152/CTLA-4-BIOT |
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| MBS673515-05mg | MyBiosource | 0.5mg | 345 EUR |
Hamster Anti-Mouse CD152/CTLA-4-BIOT |
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| MBS673515-5x05mg | MyBiosource | 5x0.5mg | 1395 EUR |
Hamster Anti-Mouse CD152/CTLA-4-UNLB |
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| MBS673518-05mg | MyBiosource | 0.5mg | 305 EUR |
Hamster Anti-Mouse CD152/CTLA-4-UNLB |
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| MBS673518-5x05mg | MyBiosource | 5x0.5mg | 1225 EUR |
Anti-human CTLA-4/CD152 Monoclonal Antibody |
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| MBS418456-01mg | MyBiosource | 0.1mg | 410 EUR |
Anti-human CTLA-4/CD152 Monoclonal Antibody |
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| MBS418456-5x01mg | MyBiosource | 5x0.1mg | 1585 EUR |
Anti-mouse CTLA-4/CD152 Monoclonal Antibody |
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| MBS418457-01mg | MyBiosource | 0.1mg | 410 EUR |
Anti-mouse CTLA-4/CD152 Monoclonal Antibody |
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| MBS418457-5x01mg | MyBiosource | 5x0.1mg | 1585 EUR |
Anti-Human CD152 (CTLA-4) SAFIRE Purified |
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| MBS696969-01mg | MyBiosource | 0.1mg | 325 EUR |
Anti-Human CD152 (CTLA-4) SAFIRE Purified |
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| MBS696969-05mg | MyBiosource | 0.5mg | 510 EUR |
Anti-Human CD152 (CTLA-4) SAFIRE Purified |
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| MBS696969-5x05mg | MyBiosource | 5x0.5mg | 2260 EUR |
Anti-Mouse CD152 (CTLA-4) SAFIRE Purified |
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| MBS696973-01mg | MyBiosource | 0.1mg | 250 EUR |
Anti-Mouse CD152 (CTLA-4) SAFIRE Purified |
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| MBS696973-5x01mg | MyBiosource | 5x0.1mg | 1080 EUR |
CONCLUSIONS
Among 77 suspected circumstances of acute ST with IgM ELISA positivity and 49 IgM damaging sufferers, 42 and seven have been optimistic, respectively, for O. tsutsugamushi 56-kDa type-specific gene in actual time PCR package. Until ST IFA, the gold normal diagnostic take a look at, is correctly validated in India, analysis of acute ST will depend upon each ELISA and quantitative PCR.
Validation of MAX Aqueous Extraction on Veratox® for Total Aflatoxin ELISA Test Kit.
Neogen Corp. (Lansing, MI) has developed a widespread aqueous extraction methodology for the detection of mycotoxins within the ELISA or lateral move format.
The Veratox® for Total Aflatoxin ELISA extraction methodology makes use of a MAX 2 extraction packet and water in substitute of historically used natural solvents. Veratox for Total Aflatoxin has a detection vary of 5-50 ppb neat or as much as 300 ppb with dilution.
The package improvement centered on superior cross-reactivity, skill to precisely detect naturally contaminated samples, and utilization of an aqueous extraction methodology.
In two separate validation research, the Veratox for Total Aflatoxin take a look at package resulted in common yields of 91-114% in naturally contaminated mycotoxin reference materials corn. The cross-reactivity profiles for aflatoxins B1, B2, G1, and G2 have been 100, 113, 103, and 93%, respectively. This package is accepted by the Grain Inspection, Packers, and Stockyards Administration.